The aminopenicillins have been used for a wide range of infections in
various species. FDA-approved
indications/species as well as non-approved uses are listed in the
Dosages section below.PAmoxicillin trihydrate is relatively
stable in the presence of gastric acid. After oral administration it
is about 74-92% absorbed in humans and animals
(monogastric). Food will decrease the rate but not the extent of oral
absorption and many clinicians suggest giving the drug with
food particularly if there is concomitant associated GI distress.
Amoxicillin serum levels will generally be 1.5-3 times greater
than those of ampicillin after equivalent oral doses.